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Research Progress
All CRC BID research projects follow a six-phase pathway from initiation to commercialisation and each project must generate sufficient objective data for review by the Strategy and Communications Committee (SACC) before it may progress to the next phase.
The six project phases are:
1. Design
Includes development of specification, modelling of processes and market analysis.
2. Measure
May include data collection, synthesis of precursors and testing of components with measuring equipment.
3. Realise
Demonstrate Proof of Principle and determine if resources are justified for full evaluation.
4. Verify
Extensive testing of systems, tracers and simulations of operational conditions. May include toxicology.
5. Validate
Testing of full concept and construction of prototype instrument in pre-production and field trials. May include human studies and live animal imaging.
6. Deploy
Conduct clinical trials and/or seek commercialisation partner.
Using this sequential approach, a set of molecules or design solutions are progressively filtered to give products that can be deployed. Within each project, at any one time, there are several sub-projects corresponding to individual molecules or detector components. These sub-projects can be at various phases.
Progress to Date
Project 1.1 Protein biosynthetic pathway targeting for PET imaging
Commencement date: September 2005
Target completion date: December 2010
Current project phase:
Fluoroethyltyrosine (FET) – DEPLOY
Other amino acids – DESIGN through REALISE
Project 1.2 Neuroreceptor ligand targeting for PET imaging
Commencement date: September 2005
Target completion date: December 2011
Current project phase:
Flumazenil - VALIDATE
Project 1.3 Development of novel receptor-based radiopharmaceuticals
Commencement date: January 2006
Target completion date: December 2011
Current project phase:
Several molecules - DESIGN
Project 1.4 Apoptotic pathway targeting for PET imaging
Commencement date: January 2006
Target completion date: June 2012
Current project phase:
Annexin – MEASURE
Other molecules - DESIGN
Project 1.5 Development of synthesis modules for tracer production
Commencement date: January 2006
Target completion date: June 2012
Reuse of 18O water – MEASURE
Other sub-projects - DESIGN
Project 2.1 High purity germanium (HPGe) strip detector
Commencement date: September 2005
Target completion date: July 2011
Current project phase: DESIGN
Project 2.2 Pixel array detector
Commencement date: July 2005
Target completion date: July 2012
Current project phase: DESIGN through MEASURE
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